Hospital Clínica Bíblica

    Revisión Bibliográfica

    Papel de las neurotrofinas en la clínica, prevención y manejo de la enfermedad de Parkinson: una revisión bibliográfica, 2023

    Edición XXVI Enero - Abril 2024

    DOI: https://doi.org/10.55139/TFRF1487


    Yazlin Alvarado Rodríguez
    Gerente de Docencia e Investigación, Hospital Clínica Bíblica, San José, Costa Rica.

    Álvaro Lazo Sevilla
    Estudiante de último año de la Carrera de Medicina y Cirugía, Universidad Hispanoamericana, San José, Costa Rica.


    Resumen

    Las neurotrofinas son una familia de moléculas encargadas de potenciar la neuroplasticidad y mantener la función neuronal a largo plazo. Los estudios en modelos animales demuestran la importancia de estas moléculas en la génesis de los trastornos neurodegenerativos, por lo que es relevante entender su papel en el manejo y prevención de la enfermedad de Parkinson.


    Palabras claves

    Enfermedad de Parkinson, BDNF, GDNF, Neurotrofina, Cribado, Prevención, Tratamiento.

    Abstract

    Neurotrophins are a family of molecules that promote neuroplasticity and maintain neuronal function over the long term. Studies in animal models have demonstrated the importance of these molecules in the pathogenesis of neurodegenerative disorders, making it important to understand their role in the management and prevention of Parkinson’s disease..


    Keywords

    Parkinson’s disease, BDNF, GDNF, Neurotrophins, Screening, Prevention, Treatment.

    Bibliografía


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