Uso de Nanotecnología en la lucha contra la diseminación de patógenos: La alternativa de Crystalusion

Avixely Vargas Blanco
Clínica Bíblica, San José, Costa Rica.

Martha Ulate Zúñiga
Clínica Bíblica, San José, Costa Rica.

María Gabriela Rodriguez Fonseca
Quantum Nanomedical Solutions, San José, Costa Rica.

María José Morera Gómez
Quantum Nanomedical Solutions, San José, Costa Rica.

Christian García Chávez
Quantum Nanomedical Solutions, San José, Costa Rica.

Esteban Zavaleta Monestel
Clínica Bíblica, San José, Costa Rica.

Resumen

El uso de la nanotecnología en el sector salud puede ofrecer una solución alterna a la creciente y preocupante propagación de virus y bacterias, la carga de las infecciones asociadas a la atención en salud y la resistencia antimicrobiana. Objetivo: indagar sobre el uso de nanotecnología en el ámbito de la salud y describir las cualidades del producto “Crystalusion”. Método: Se llevó a cabo una revisión bibliográfica con la metodología PRISMA, en la que se incluyeron 34 artículos de acceso libre de los últimos 10 años, en las bases de datos PubMed, Science Direct, ASM Journals, Lilacs y ProQuest, más reportes de Nanomedical. Resultados: Los desinfectantes de uso común en los centros de salud, principalmente los de base alcohólica muestran graves desventajas en su uso, principalmente su corta actividad biocida, su lesividad a la piel y su incompetencia ante microorganismos resistentes. La nanotecnología ofrece soluciones alternativas a estos problemas, con materiales que resultan menos lesivos para la piel, con actividad biocida de liberación continua, blancos específicos, mejor solubilidad, menor toxicidad y baja probabilidad de resistencia microbiana. Conclusiones: Productos a base de nanotecnología, como Crystalusion ofrecen ventajas significativas respecto a los de uso actual, en la prevención y control de infecciones, sin embargo, resaltan la necesidad de una mejor evaluación de la bioseguridad e impacto ambiental en su diseño.

Palabras claves

Nanotecnología, Nanopartículas, Cristales Líquidos, Desinfectante, Desinfectantes para las manos, Control de Infecciones.

Abstract

The use of nanotechnology in the healthcare sector may offer an alternative solution to the increasing and worrisome spread of viruses and bacteria, the burden of healthcare-associated infections, and antimicrobial resistance. Objective: to investigate the use of nanotechnology in health care and to describe the qualities of the product “Crystalusion”. Methods: A literature review was carried out using PRISMA methodology, including 34 open-access articles from the last 10 years in the databases PubMed, Science Direct, ASM Journals, Lilacs, and ProQuest. Results: The disinfectants commonly used in health centers, mainly those with an alcoholic base, show serious disadvantages in their use, mainly their short biocidal activity, their harmfulness to the skin, and their incompetence in the face of resistant microorganisms. Nanotechnology offers alternative solutions to these problems, with materials that are less harmful to the skin, with continuous release biocidal activity, specific targets, better solubility, lower toxicity, and low probability of microbial resistance, some of which are already in use in the market, such as Crystalusion, and others that require further research. Conclusions: Nanotechnology-based products, such as Crystalusion, offer significant advantages over those in current use, in infection prevention and control, however, they highlight the need for better biosafety and environmental impact assessment in their design.

Keywords

Bibliografía

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